Cytologic diagnosis of rhinoscleroma

The cytologic diagnosis of a case of rhinoscleroma was made on brushing specimens of a laryngeal lesion. The cytologic picture included aggregates of the characteristic Mikulicz cells, large, rounded histiocytes with an eccentric nucleus and vacuolar cytoplasm containing the short rods of Klebsiella rhinoscleromatis. Although the diagnosis of this chronic infectious disease involving the upper respiratory tract is routinely made by tissue biopsy and bacteriologic study of the lesions, the present report indicates that cytology has a definite place in its diagnosis.