Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Blood-brain interfaces in vertebrates: a comparative approach.

H F Cserr, M Bundgaard

    The American Journal of Physiology
    |March 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The use of acupuncture in controlling the gag reflex in patients requiring an upper alginate impression: an audit.

    British dental journal·2006
    Same author

    Blood donation and acupuncture.

    British dental journal·2003
    Same author

    Short-term results after aortic valve replacement with stentless xenografts in elderly patients.

    Scandinavian cardiovascular journal : SCJ·2001
    Same author

    Transport of protons and lactate in cultured human fetal retinal pigment epithelial cells.

    Pflugers Archiv : European journal of physiology·2000
    Same author

    Antigen-dependent intrathecal antibody synthesis in the normal rat brain: tissue entry and local retention of antigen-specific B cells.

    Journal of immunology (Baltimore, Md. : 1950)·1998
    Same author

    Growth of P511 mastocytoma cells in BALB/c mouse brain elicits CTL response without tumor elimination: a new tumor model for regional central nervous system immunity.

    Journal of immunology (Baltimore, Md. : 1950)·1997

    All vertebrates possess brain barrier membranes, including the blood-brain barrier, choroid plexus, and meningeal barrier, which maintain a unique neuronal environment. These membranes exhibit conserved structures and functions across vertebrate classes, optimizing neuronal communication.

    Area of Science:

    • Neuroscience
    • Comparative Physiology
    • Cell Biology

    Background:

    • The vertebrate brain's neuronal microenvironment is protected from plasma by specialized membranes.
    • These include the blood-brain barrier, choroid plexus, and meningeal barrier.

    Purpose of the Study:

    • To review the structure and function of vertebrate brain barrier membranes across different classes.
    • To explore the phylogenetic development and functional significance of these barriers.

    Main Methods:

    • Comparative analysis of existing literature on brain barrier structures and functions.
    • Review of studies on tight junctions, transport mechanisms, and epithelial properties.

    Main Results:

    • All vertebrates possess brain barrier membranes with fundamentally similar functional characteristics.

    Related Experiment Videos

  • The blood-brain barrier and meningeal barrier exhibit tight epithelial properties.
  • The choroidal epithelium functions as a secretory epithelium.

    • Conclusions:

    • The phylogenetic development of the blood-brain barrier created an optimal extracellular milieu for neuronal communication.
    • Specialized brain barrier membranes are crucial for maintaining the unique neuronal environment in vertebrates.