Method of computed tomography-based stereotactic biopsy with arteriographic control

Area of Science:

• Neurosurgery
• Medical Imaging
• Oncology

Background:

• Intracranial neoplasms require accurate biopsy for diagnosis and treatment planning.
• Stereotactic biopsy offers precise targeting of brain lesions.
• Integrating imaging modalities enhances procedural safety and accuracy.

Purpose of the Study:

• To describe a novel method for computed tomography (CT)-based stereotactic biopsy of intracranial neoplasms.
• To incorporate arteriographic control for identifying safe, avascular trajectories.
• To evaluate the safety and efficacy of this combined stereotactic biopsy technique.

Main Methods:

• Utilizing stereotactic CT and digitized stereotactic arteriographic data.
• Inputting data into a 3D computer matrix aligned with the stereotactic frame's coordinate system.
• Selecting biopsy sites via cursor on CT display and calculating frame adjustments for precise targeting.
• Determining horizontal and vertical approach angles from arteriograms to ensure avascular pathways.

Main Results:

• The described CT-based stereotactic biopsy with arteriographic control was successfully applied in 86 patients.
• The procedure demonstrated zero morbidity or mortality.
• Accurate targeting and safe avascular trajectory identification were achieved.

Conclusions:

• CT-based stereotactic biopsy with arteriographic control is a safe and effective method for intracranial neoplasms.
• This technique minimizes risks by identifying avascular trajectories.
• The procedure offers a reliable approach for obtaining tissue samples from deep-seated brain lesions.