Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Does prostacyclin prevent cognitive deficits after open heart surgery?

E Pears, R Bowman, J Kincey

    Psychological Medicine
    |February 1, 1984
    PubMed
    Summary

    This study found no significant cognitive benefits from prostacyclin in open heart surgery patients. A visual retention deficit was observed in the prostacyclin group, challenging prior research.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Assessing the Relative Importance of Satellite-Detected Methane Superemitters in Quantifying Total Emissions for Oil and Gas Production Areas in Algeria.

    Environmental science & technology·2023
    Same author

    Visual outcomes and predictors in optic pathway glioma: a single centre study.

    Eye (London, England)·2022
    Same author

    Sensory experiences and cues among E-cigarette users.

    Harm reduction journal·2020
    Same author

    High-resolution computed tomography evaluation of congenital aural atresia - how useful is this?

    The Journal of laryngology and otology·2020
    Same author

    Re: Clarification related to the commentary titled, ?SThe inappropriate use of formulae and references and the possible domino effect of spurious results?? written by Gautam et al. 2019.

    Preventive veterinary medicine·2019
    Same author

    Cemented Exeter total hip arthroplasty with a 32 mm head on highly crosslinked polyethylene: Does age influence functional outcome, satisfaction, activity, stem migration, and periprosthetic bone mineral density?

    Bone & joint research·2019

    Area of Science:

    • Cardiology
    • Neurology
    • Pharmacology

    Background:

    • Open heart surgery can impact cognitive function.
    • Prostacyclin has been investigated for potential neuroprotective effects.
    • Previous studies suggested prostacyclin may mitigate cognitive decline post-surgery.

    Purpose of the Study:

    • To evaluate the effect of prostacyclin on cognitive function in open heart surgery patients.
    • To compare cognitive outcomes between patients receiving prostacyclin and placebo.
    • To reassess the efficacy of prostacyclin in preventing post-operative cognitive deficits.

    Main Methods:

    • Two groups of open heart surgery patients were studied: one receiving prostacyclin, the other a placebo.
    • Cognitive functions were assessed using a battery of clinical tests.

    Related Experiment Videos

  • Assessments were conducted one week pre-operatively and three months post-operatively.

    • Main Results:

    • No significant overall differences in cognitive function were detected between the prostacyclin and placebo groups.
    • A specific visual retention deficit was identified in the prostacyclin group at the 3-month follow-up.
    • This finding contrasts with previous research suggesting cognitive benefits.

    Conclusions:

    • Prostacyclin does not appear to reduce cognitive deficits following open heart surgery.
    • The observed visual retention deficit warrants further investigation.
    • Current evidence casts doubt on the utility of prostacyclin for cognitive protection in this patient population.