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Related Experiment Videos

[A field experiment using E. coli-K99 vaccine].

G H Wentink, C Holzhauer

    Tijdschrift Voor Diergeneeskunde
    |March 15, 1984
    PubMed
    Summary

    Vaccinating pregnant dairy cows with an E. coli-K99 antigen vaccine boosted immunoglobulin levels in colostrum, aiding calf health. This, alongside other measures, helped resolve calf scours in affected herds.

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    Veterinary microbiology·2004

    Area of Science:

    • Veterinary immunology
    • Bovine calf health
    • Microbial disease control

    Background:

    • Calf scours, often caused by E. coli-K99, is a significant issue in dairy herds.
    • Maternal vaccination can transfer immunity to offspring via colostrum.

    Purpose of the Study:

    • To evaluate the efficacy of an E. coli-K99 antigen vaccine in pregnant dairy cows.
    • To assess the impact of vaccination on immunoglobulin levels in colostrum and calf health.

    Main Methods:

    • Field experiment involving pregnant dairy cows, with vaccination or placebo administration.
    • Measurement of immunoglobulin concentrations in colostrum.
    • Monitoring of calf health and isolation of E. coli-K99.

    Main Results:

    • Vaccinated cows produced colostrum with significantly higher E. coli-K99 specific immunoglobulins.
    • Severe scouring resolved in calves from both vaccinated and control groups.
    • E. coli-K99 was no longer isolatable from calves after the intervention.

    Conclusions:

    • Maternal vaccination with E. coli-K99 antigen is a viable strategy to increase colostral immunity.
    • Combined zootechnical measures and vaccination appear effective in controlling calf scours.
    • Further investigation into the synergistic effects of vaccination and management practices is warranted.

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