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Haemophilus aphrophilus cholecystitis.

W Huck, M R Britt

    American Journal of Clinical Pathology
    |March 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Haemophilus aphrophilus, typically found in endocarditis or brain abscesses, was unusually isolated from the gallbladder and blood of a patient with acute cholecystitis. This finding expands the known clinical relevance of this bacterium.

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    Area of Science:

    • Microbiology
    • Clinical Medicine
    • Infectious Diseases

    Background:

    • Acute cholecystitis is a common surgical condition.
    • Haemophilus aphrophilus is a bacterium rarely isolated from clinical specimens.
    • This organism is typically associated with endocarditis and brain abscesses.

    Observation:

    • Cultures from the gallbladder and blood of a 60-year-old male patient with acute cholecystitis yielded Haemophilus aphrophilus.
    • The isolation of Haemophilus aphrophilus from the gallbladder is an uncommon occurrence.

    Findings:

    • Haemophilus aphrophilus was identified as the causative agent in a case of acute cholecystitis.
    • Distinguishing Haemophilus aphrophilus from similar bacteria like Eikenella corrodens and Actinobacillus actinomycetemcomitans relies on colonial morphology and specific biochemical tests (oxidase, catalase, and fermentation of various sugars).

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    Implications:

    • This case highlights the potential for Haemophilus aphrophilus to cause infections beyond its typical presentation.
    • Further research may be warranted to understand the pathogenic mechanisms of Haemophilus aphrophilus in biliary tract infections.
    • Diagnostic laboratories should consider Haemophilus aphrophilus in the differential diagnosis of acute cholecystitis, especially when unusual organisms are suspected.