High-frequency jet ventilation vs continuous positive airway pressure for postoperative respiratory support

In ten patients after recovery from general anesthesia for major vascular surgery, we compared continuous positive airway pressure (CPAP) and high-frequency jet ventilation (HFJV) at the same fractional concentration of oxygen in the inspired gas, both being superimposed on spontaneous breathing. The HFJV was delivered by a ventilator ( Acutronic VS-600) through the lateral lumen of a three-lumen endotracheal tube. Mean airway pressure was increased (3, 8, and 11 mm Hg) by adjusting the driving pressure during HFJV and by the setting of the expiratory valve during CPAP. During HFJV, the frequency (10 Hz) and inspiratory-expiratory ratio (0.25) were kept constant. Control values were measured when patients breathed spontaneously without positive end-expiratory pressure. Cardiac output and transmural filling pressures remained unchanged throughout the study. Neither the arterial oxygen pressure (PaO2) nor intrapulmonary shunt (Qs/Qt) changed significantly during CPAP. The 20- to 30-percent increase in PaO2 and the 5- to 10-percent decrease in Qs/Qt during HFJV when compared to control reflected a slightly but significantly (p less than 0.05) better oxygenation. The increase in arterial carbon dioxide tension was significantly greater during CPAP than during HFJV.