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Calcium ions protect cell-substratum adhesion receptors against proteolysis. Evidence from immunoabsorption and
Experimental Cell Research
|June 1, 1984
Abstract:
An antibody preparation against BHK cell wheat germ agglutinin receptors (anti-WGA-R), which inhibits fibronectin-mediated cell adhesion, was characterized by immunoabsorption and electroblotting experiments. The results indicated that a 48 kD cell surface WGA-R receptor is protected from proteolysis by Ca2+ ions and is important in fibronectin-mediated cell adhesion.