The site of renin in the human uterus

Renin has been known to be present in the human uterus for many years. The study reported in this paper deals with the identification of the site of renin in the human uterus by the peroxidase-antiperoxidase technique, using anti-human renin. Cells containing renin granules have been demonstrated only in patients complaining of menorrhagia. The cells occur singly and in clusters in the interarteriolar connective tissue within myometrium adjacent to the endometrium. The cells bear a striking resemblance to those of the juxta-glomerular apparatus of the kidney.