Related Experiment Videos
Bindii (Jo Jo) dermatitis (Soliva pterosperma [Compositae])
Insights
Bindii dermatitis, a skin rash in Australian children, is caused by bindii seed exposure. Testing confirmed bindii seed pricking reproduces the characteristic rash, suggesting an allergic reaction.
Area of Science:
- Dermatology
- Pediatrics
- Allergology
Background:
- Bindii dermatitis presents as a distinct skin eruption in Australian children.
- The condition is characterized by erythematous papules with puncta, primarily on the palms, soles, and knees.
- It typically occurs during the spring and early summer months.
Purpose of the Study:
- To investigate the causative agent of bindii dermatitis.
- To determine the pathogenesis of this specific skin condition.
- To differentiate between an allergic reaction and a foreign body response.
Main Methods:
- Intradermal skin pricking with bindii seed was performed on affected children and controls.
- Lesional reactions were observed and documented within 48 hours.
- Clinical presentation and reaction patterns were compared between groups.
Main Results:
- Three children with bindii dermatitis developed an erythematous, indurated papule within 48 hours of bindii seed pricking.
- Control subjects (thirteen) did not exhibit similar reactions.
- The induced lesion mimicked the primary clinical presentation of bindii dermatitis.
Conclusions:
- The findings suggest bindii seed is the direct cause of bindii dermatitis.
- Pathogenesis likely involves an allergic reaction to retained bindii seed antigen.
- This contrasts with a simple nonspecific foreign body injury reaction.
Abstract:
Bindii dermatitis is a distinctive eruption occurring in some Australian children during spring and early summer and characterized by discrete erythematous papules with puncta, concentrated over the palms, soles, and knees. In three affected individuals (but not in thirteen controls), pricking the skin with bindii seed produced an erythematous, indurated papule that appeared within 48 hours of intradermal pricking and simulated the primary lesion. Pathogenesis may involve an allergic reaction with a retained depot of antigen rather than a nonspecific foreign body injury reaction.