Related Experiment Video
Updated: Aug 14, 2026

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo
Published on: July 1, 2013
Collagen production and types in fibrous capsules around breast implants
Abstract:
This study demonstrates that increased collagen production but not an altered ratio of type III:I collagen is associated with breast capsular contracture. From these findings and previous data, therefore, it appears that capsular contracture is associated with increased foreign-body response biochemically as well as histologically. Further studies are required to directly assess the reasons for contraction around some implants and not others; however, it appears that control of capsular contracture may be achieved by controlling biochemical as well as cellular events associated with contraction. Such studies remain to be done.
Related Concept Videos
Collagens are the Major Structural Proteins of ECM
Connective tissue proper includes loose...
Fibril-associated Collagen
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
Matrix Proteoglycans and Glycoproteins
Type IV Collagen of Basal Lamina
A type IV collagen molecule has six alpha chains which can exist in...
Phases of Wound Repair
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Extracellular Matrix

