Gastrointestinal tract complications of diabetes mellitus. Pathophysiology and management

Diabetes mellitus can affect every organ system, including large and small blood vessels, eyes, nerves, kidneys, and the gastrointestinal (GI) tract. We reviewed recent knowledge concerning the impact of diabetes on the gut. While the incidence of GI tract complications is usually considered relatively low, functional alterations have been demonstrated at every level in the gut and account for considerable morbidity in the diabetic population.