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Pharmacokinetic data processed by microcomputer for the formulation of optimal drug dosage form
European Journal of Drug Metabolism and Pharmacokinetics
|April 1, 1984
Abstract:
Microcomputers have been used in pharmacokinetics for several years, but their use in the area of formulation is a new application. By using appropriate data on the drug, the dosage form required and its mechanism of absorption and clearance, microcomputers can systematize and speed-up formulation, simplify manufacturing processes and, through simulated models and plasma level predictions, reduce the number of bioavailability studies needed.