Fibronectin as an opsonic regulator of monocyte phagocytosis

Experiments using human monocytes and the yeast Saccharomyces cerevisiae have shown that fibronectin is a major plasma opsonin. Further studies have shown that fibronectin promotes the ingestion as well as the adherence of micro-organisms. These observations are independent of the non-physiological concentrations of heparin used in other assay systems.