Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prostatic acid phosphatase: current concepts.

N A Romas

    Seminars in Urology
    |August 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Antibodies to prostatic acid phosphatase (PAP) enable better detection of the enzyme. Labeled PAP antibodies show promise for detecting and potentially treating prostate cancer metastases.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Sex hormone-binding globulin is synthesized in target cells.

    The Journal of endocrinology·2002
    Same author

    Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane.

    The Journal of steroid biochemistry and molecular biology·1999
    Same author

    Androgen and estrogen signaling at the cell membrane via G-proteins and cyclic adenosine monophosphate.

    Steroids·1999
    Same author

    Efficacy of finasteride is maintained in patients with benign prostatic hyperplasia treated for 5 years. The North American Finasteride Study Group.

    Urology·1999
    Same author

    Treatment with finasteride preserves usefulness of prostate-specific antigen in the detection of prostate cancer: results of a randomized, double-blind, placebo-controlled clinical trial. PLESS Study Group. Proscar Long-term Efficacy and Safety Study.

    Urology·1998
    Same author

    Androgens, estrogens, and second messengers.

    Steroids·1998

    Area of Science:

    • Immunology
    • Oncology
    • Biochemistry

    Background:

    • Prostatic acid phosphatase (PAP) is a key biomarker in prostate cancer.
    • Antibody development has significantly advanced PAP detection methods.
    • Previous methods for PAP detection had limitations.

    Purpose of the Study:

    • To review the advantages and limitations of antibody-based PAP detection.
    • To explore novel applications of PAP antibodies in cancer diagnostics and therapeutics.
    • To assess the potential of radiolabeled PAP antibodies for imaging prostate cancer metastases.

    Main Methods:

    • Review of existing literature on PAP antibodies.
    • Discussion of antibody-based detection methodologies.
    • Exploration of radioimmunodetection techniques using PAP antibodies.

    Related Experiment Videos

    Main Results:

    • Antibodies to PAP have revolutionized its detection in serum and tissue.
    • Radioactive labeling of PAP antibodies offers a new approach for radioimmunodetection.
    • Potential for PAP antibodies in targeted therapy for metastatic prostate cancer.

    Conclusions:

    • PAP antibodies represent a significant advancement in prostate cancer diagnostics.
    • Radioimmunodetection using labeled PAP antibodies shows promise for localizing metastases.
    • Further research may establish PAP antibodies as a therapeutic tool in oncology.