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Diclofenac (Voltaren). Pain-relieving effect after tonsillectomy.

H Dommerby, O R Rasmussen

    Acta Oto-Laryngologica
    |July 1, 1984
    PubMed
    Summary

    Diclofenac suppositories significantly reduced postoperative pain and improved general condition in patients, demonstrating a 50% therapeutic gain. This led to its adoption in ENT departments.

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    Area of Science:

    • Pharmacology
    • Clinical Medicine
    • Pain Management

    Background:

    • Postoperative pain management is crucial for patient recovery.
    • Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for pain relief.

    Purpose of the Study:

    • To evaluate the efficacy of diclofenac suppositories in managing postoperative pain.
    • To compare diclofenac treatment against a placebo in a controlled clinical setting.

    Main Methods:

    • A two-center, double-blind, placebo-controlled study was conducted.
    • 97 patients received either 100 mg diclofenac (followed by 50 mg twice daily) or placebo suppositories postoperatively.
    • Efficacy was assessed using visual analogue scales by patients and staff.

    Main Results:

    • Diclofenac demonstrated a statistically significant reduction (p < 0.001) in pain associated with swallowing.
    • A significant improvement in the general condition of patients treated with diclofenac was observed.
    • A therapeutic gain of 50% was calculated for diclofenac treatment.

    Conclusions:

    • Diclofenac suppositories are effective in alleviating postoperative pain and improving patient well-being.
    • The study results support the use of diclofenac in postoperative care within ENT departments.

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