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Testing for autonomic neuropathy.

J Hilsted

    Annals of Clinical Research
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Diabetic autonomic neuropathy is common, but hard to diagnose early. This review covers new nerve function tests and suggests diagnostic criteria for better detection.

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    Area of Science:

    • Endocrinology
    • Neurology
    • Diabetology

    Background:

    • Autonomic neuropathy is a frequent complication of long-term diabetes mellitus.
    • Clinical symptoms often manifest late and are nonspecific, complicating early diagnosis.
    • Approximately 30% of diabetic patients exhibit autonomic dysfunction signs after 10 years.

    Purpose of the Study:

    • To review recently developed, quantifiable autonomic nerve function tests (ANFTs).
    • To emphasize the physiological basis and practical applicability of these ANFTs.
    • To propose diagnostic criteria for diabetic autonomic neuropathy based on ANFTs.

    Main Methods:

    • Review of current literature on autonomic nerve function tests.
    • Analysis of the physiological underpinnings of selected ANFTs.

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  • Evaluation of the clinical utility and reproducibility of ANFTs.

    • Main Results:

    • Several quantifiable and reproducible ANFTs have been developed.
    • These tests offer objective measures of autonomic nervous system function in diabetes.
    • The review highlights the practical aspects and physiological basis of these diagnostic tools.

    Conclusions:

    • Diabetic autonomic neuropathy diagnosis is challenging due to late and nonspecific symptoms.
    • Newly developed ANFTs provide objective and reproducible methods for assessment.
    • Suggested diagnostic criteria using ANFTs aim to improve early and accurate detection.