Hepatic manifestations of lymphomas

The various hepatic manifestations of malignant lymphomas are discussed as well as the methods employed to detect hepatic involvement in those diseases. Hepatomegaly is infrequent in early Hodgkin's disease and, when present, may represent a nonspecific reactive phenomenon. Hepatomegaly is more common in non-Hodgkin's lymphomas and various leukemias and usually represents neoplastic involvement of that organ. Radiographic procedures and liver function studies are unreliable in detecting liver involvement although correlation of the various data increases diagnostic accuracy. Morphological manifestations of these diseases are discussed as well as those methods which are best suited for diagnosis.