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Cardiovascular disease and work place exposures.

K D Rosenman

    Archives of Environmental Health
    |May 1, 1984
    PubMed
    Summary

    Occupational studies often focus on cancer, but reviewing cardiovascular mortality is crucial. Research in the rubber industry highlights links between solvents like phenol and ethanol and heart disease, necessitating further investigation.

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    Area of Science:

    • Occupational health
    • Epidemiology
    • Cardiovascular disease research

    Background:

    • Occupational cohort studies traditionally emphasize cancer mortality.
    • Cardiovascular mortality patterns in occupational settings require further systematic review.
    • The 'healthy worker effect' often shows reduced cardiovascular mortality, but specific exposures warrant deeper investigation.

    Purpose of the Study:

    • To systematically review cardiovascular mortality in occupational cohort studies.
    • To identify occupational exposures linked to heart disease.
    • To assess the utility of occupational disease surveillance for cardiovascular research.

    Main Methods:

    • Systematic literature review of occupational cohort studies.
    • Analysis of cardiovascular disease mortality data.
    • Follow-up study in the rubber industry.

    Main Results:

    • A study in the rubber industry indicated excess coronary artery heart disease (CAHD) mortality.
    • Confirmed association between carbon disulfide and atherosclerosis.
    • Suggested new causal links between CAHD and phenol/ethanol solvent use.

    Conclusions:

    • Systematic reviews of cardiovascular mortality in occupational settings are valuable.
    • Specific exposures like phenol and ethanol may be associated with heart disease.
    • Further research is needed to evaluate occupational exposures and cardiovascular health protection.

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