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Survival after prolonged persistent pulmonary hypertension
Insights
Persistent pulmonary hypertension in infants (PPHN) can resolve spontaneously. Continued supportive care, like assisted ventilation, is crucial for PPHN patients without other complications, as recovery may occur later.
Area of Science:
- Neonatology
- Pediatric Cardiology
- Pulmonary Medicine
Background:
- Persistent pulmonary hypertension (PPH) is a serious condition in newborns.
- Infants with PPH often require intensive respiratory support.
Observation:
- A case of prolonged PPH in an infant is presented.
- The infant did not respond to conventional mechanical and pharmacological treatments.
Findings:
- Spontaneous improvement in the infant's condition was observed at 13 days of age.
- This suggests a potential for delayed recovery in PPH.
Implications:
- Assisted ventilation should be maintained in PPH cases without major cardiac or pulmonary abnormalities.
- Continued supportive care is vital, as recovery can occur unexpectedly in PPH.
Abstract:
We report an infant with prolonged persistent pulmonary hypertension (PPH) who failed to respond to various mechanical and pharmacological therapies but who showed spontaneous improvement at 13 days of age. We therefore stress that assisted ventilation should be continued in PPH without major structural cardiac or pulmonary abnormality or ongoing iatrogenic complications, as recovery may occur at any time.