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Calcium and osteoporosis.

L V Avioli

    Annual Review of Nutrition
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Adequate calcium intake is crucial for bone health, potentially preventing osteoporosis. Early dietary intervention in adulthood can mitigate age-related bone loss and reduce fracture risk in aging populations.

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    Area of Science:

    • Gerontology
    • Nutritional Science
    • Bone Biology

    Background:

    • Osteoporosis pathogenesis is complex and poorly understood.
    • Age-related changes in bone cell function, hormone secretion, and metabolism contribute to skeletal fragility.
    • An aging population faces increasing rates of fractures due to osteoporosis.

    Purpose of the Study:

    • To investigate the role of calcium in modulating skeletal response to aging.
    • To emphasize the importance of adequate calcium supply for bone health.
    • To advocate for early dietary intervention to prevent age-related bone loss.

    Main Methods:

    • Review of existing literature on calcium metabolism and bone health.
    • Analysis of the impact of calcium balance on skeletal mass.

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  • Correlation of calcium supplementation with bone mass improvements in menopausal women.

    • Main Results:

    • Calcium deficiency and malabsorption are implicated in osteoporosis development.
    • Calcium supplements improve calcium balance and correlate with increased skeletal mass in perimenopausal and postmenopausal women.
    • Calcium replacement may slow bone resorption but not reverse existing bone loss.

    Conclusions:

    • Focusing on diets and calcium supplements for adequate mineral supply is desirable.
    • Dietary analysis and calcium intake modification in the third and fourth decades of life are recommended.
    • Early intervention aims to retard age-related skeletal tissue loss and reduce fracture risk.