Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Differential blood cell separation using a high gradient magnetic field.

F Paul, S Roath, D Melville

    British Journal of Haematology
    |February 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    An autoantibody signature predictive for multiple sclerosis: evidence at the protein level and association with histopathological lesion types.

    Journal of neurology·2026
    Same author

    Management and burden of disease in people with myelin oligodendrocyte glycoprotein antibody-associated disease: data from an international, cross-sectional survey.

    Journal of neurology·2025
    Same author

    Rapid differentiation of MOGAD and MS after a single optic neuritis.

    Journal of neurology·2024
    Same author

    Impact of sex on clinical outcome in early Multiple Sclerosis.

    Multiple sclerosis and related disorders·2024
    Same author

    Improving the sensitivity of myelin oligodendrocyte glycoprotein-antibody testing: exclusive or predominant MOG-IgG3 seropositivity-a potential diagnostic pitfall in patients with MOG-EM/MOGAD.

    Journal of neurology·2024
    Same author

    A massive rock and ice avalanche caused the 2021 disaster at Chamoli, Indian Himalaya.

    Science (New York, N.Y.)·2021
    Same journal

    Author response to Zhang and Chen.

    British journal of haematology·2026
    Same journal

    Response-adapted chimeric antigen receptor T cell (CAR-T)-sparing consolidation radiotherapy in high-risk large B-cell lymphoma (LBCL): Results of the prospective RESTART protocol.

    British journal of haematology·2026
    Same journal

    Prospective, multicentre phase II study to evaluate the clinical benefit of reduced-dose lenalidomide and dexamethasone based on frailty stratification in elderly, unfit patients with newly diagnosed multiple myeloma.

    British journal of haematology·2026
    Same journal

    Real-world effectiveness and safety of acalabrutinib in chronic lymphocytic leukaemia: Multicentre experience.

    British journal of haematology·2026
    Same journal

    Novel germline GATA1s-generating variant associates with somatic STAG2 variants in hypoplastic myelodysplastic neoplasm.

    British journal of haematology·2026
    Same journal

    The Endothelial Activation and Stress Index (EASIX) at diagnosis is associated with survival in primary central nervous system lymphoma.

    British journal of haematology·2026
    See all related articles

    This study introduces a novel magnetic separation technique for erythrocytes (red blood cells) using reduced hemoglobin

    Area of Science:

    • Biomedical Engineering
    • Hematology
    • Biophysics

    Background:

    • Erythrocyte separation is crucial for various medical and research applications.
    • Existing methods may lead to cell damage or contamination.
    • Exploiting intrinsic cellular properties offers a promising avenue for improved separation.

    Purpose of the Study:

    • To develop and characterize a novel technique for separating erythrocytes from whole blood.
    • To investigate the efficacy of magnetic separation based on reduced hemoglobin properties.
    • To assess the impact of the separation process on erythrocyte integrity.

    Main Methods:

    • A filter composed of stainless steel wire mesh within an electromagnet was designed.
    • The electromagnet generated a magnetic field gradient to trap erythrocytes.

    Related Experiment Videos

  • Experiments varied magnetic field strength (0-1.4 Tesla) and flow rates (1.9-12.9 x 10(-4) m s(-1)).

    • Main Results:

    • Erythrocytes were successfully captured and separated using the magnetic filter.
    • Capture efficiency correlated with applied magnetic field strength and flow rate.
    • No significant hemolysis or surface damage to erythrocytes was observed.
    • Leukocytes and platelets were not retained by the filter.

    Conclusions:

    • The described technique offers an effective, non-damaging method for erythrocyte separation.
    • This magnetic separation method shows potential for clinical and research applications.
    • The process preserves erythrocyte viability and purity, excluding other blood components.