Asymmetrical cerebrovascular response to right and left hemisphere cortical suction lesions in the rat

We have previously demonstrated that focal lesions of the right but not left cerebral cortex in the rat produce hyperactivity and depletions of norepinephrine. To assess the cerebrovascular response to suction lesions, postoperative rats were infused intravenously with [14C]inulin. The brain inulin concentration in the right lesion group was significantly higher than control (no surgery) or left lesion groups in all cortical quandrants, but most prominently in the quadrant posterior and contralateral to the lesion site.