Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Does secretin control insulin secretion?

A V Greco, R Manna, G Ghirlanda

    Experimental and Clinical Endocrinology
    |July 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Temporal trend of drug-resistance and APOBEC editing in PBMC genotypic resistance tests from HIV-1 infected virologically suppressed individuals.

    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2023
    Same author

    Editorial - Lies have short legs.

    European review for medical and pharmacological sciences·2020
    Same author

    HIV MDR is still a relevant issue despite its dramatic drop over the years.

    The Journal of antimicrobial chemotherapy·2020
    Same author

    Dynamics and phylogenetic relationships of HIV-1 transmitted drug resistance according to subtype in Italy over the years 2000-14.

    The Journal of antimicrobial chemotherapy·2017
    Same author

    Pre-existent NRTI and NNRTI resistance impacts on maintenance of virological suppression in HIV-1-infected patients who switch to a tenofovir/emtricitabine/rilpivirine single-tablet regimen.

    The Journal of antimicrobial chemotherapy·2016
    Same author

    Virological response and resistance profile in HIV-1-infected patients starting darunavir-containing regimens.

    HIV medicine·2016
    Same journal

    Autoantibodies to glutamate decarboxylase detected in diabetes-prone BB/OK rats do not distinguish onset of diabetes.

    Experimental and clinical endocrinology·1994
    Same journal

    Urinary excretion of hydroxy-pyridinium cross-links of collagen reflects skeletal growth velocity in normal children.

    Experimental and clinical endocrinology·1994
    Same journal

    Tissue regenerates of adrenal cortex with a physiological function twelve years after bilateral total adrenalectomy for Cushing's syndrome.

    Experimental and clinical endocrinology·1994
    Same journal

    Thyroid hormone deiodination in target tissues--a regulatory role for the trace element selenium?

    Experimental and clinical endocrinology·1994
    Same journal

    Effects of music treatment on salivary cortisol in patients exposed to pre-surgical stress.

    Experimental and clinical endocrinology·1994
    Same journal

    Systolic ventricular function in acute hypothyroidism: a study using Doppler echocardiography.

    Experimental and clinical endocrinology·1994
    See all related articles

    Secretin weakly stimulates insulin release, failing to enhance arginine-induced secretion. This finding challenges secretin's role as the primary hormone in the enteroinsular axis.

    Area of Science:

    • Endocrinology
    • Gastroenterology

    Background:

    • The enteroinsular axis regulates glucose homeostasis.
    • Secretin's role in this axis is not fully understood.

    Purpose of the Study:

    • To investigate the effect of secretin on insulin release.
    • To determine if secretin potentiates arginine-induced insulin secretion.

    Main Methods:

    • Normal subjects received arginine prestimulation.
    • Secretin or glucose pulses were administered.
    • Insulin secretion was measured.

    Main Results:

    • Secretin induced a weak and brief insulin secretion.
    • Secretin did not potentiate arginine-induced insulin secretion.

    Related Experiment Videos

  • Glucose induced a stronger insulin response.

    • Conclusions:

    • Secretin is not a potent stimulator of insulin release.
    • The findings do not support secretin as the central hormone in the enteroinsular axis.