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[Lymphocytes and their subpopulations in psoriasis]
Peripheral blood lymphocytes and his subpopulations from 32 psoriatic patients were analyzed. For this, E rosettes for T cells, EAC rosettes for B cells and EA rosettes for receptors for Fc-IgM and Fc-IgG on T cells were employed. A decrease of circulating T cells is demonstrated as well an increase of null cells. No differences are observed for the number of circulating TM to TG cells (with Fc-IgM or Fc-IgG receptors). However, a decreased of T null(T/) cells was found. The authors postulate that the phenotypic appearances of T cells was associated to localize waste of modulated or activated T cells in lesions during the active phase of psoriasis.
Peripheral blood lymphocytes and his subpopulations from 32 psoriatic patients were analyzed. For this, E rosettes for T cells, EAC rosettes for B cells and EA rosettes for receptors for Fc-IgM and Fc-IgG on T cells were employed. A decrease of circulating T cells is demonstrated as well an increase of null cells. No differences are observed for the number of circulating TM to TG cells (with Fc-IgM or Fc-IgG receptors). However, a decreased of T null(T/) cells was found. The authors postulate that the phenotypic appearances of T cells was associated to localize waste of modulated or activated T cells in lesions during the active phase of psoriasis.