Related Experiment Videos
[Evaluation of immune status in gastric cancer using Su-Ps skin test]
Immunotherapy for gastric cancer has been adopted by any institutes recently. However, immunoparameters which exactly express patients' immune status have not been determined. In this study, the Su-Ps skin test was tried to evaluate whether or not this reaction could become a usable immunoparameter. Conclusions were as follows: 1) Late-stage patients showed a significantly weak response in the Su-Ps skin test compared to early-stage patients when examined preoperatively. 2) Su-Ps skin reaction became stronger after gastrectomy in early-stage patients, while the contrary result was observed in late-stage patients. 3) Postoperative Su-Ps skin tests showed a stronger response than preoperative tests regardless of the patients' stage, when patients received OK-432 treatment. The Su-Ps skin test reaction seemed to be well-correlated with the patients' immune status as above, so that this test can be chosen for evaluation of immunotherapy.
Immunotherapy for gastric cancer has been adopted by any institutes recently. However, immunoparameters which exactly express patients' immune status have not been determined. In this study, the Su-Ps skin test was tried to evaluate whether or not this reaction could become a usable immunoparameter. Conclusions were as follows: 1) Late-stage patients showed a significantly weak response in the Su-Ps skin test compared to early-stage patients when examined preoperatively. 2) Su-Ps skin reaction became stronger after gastrectomy in early-stage patients, while the contrary result was observed in late-stage patients. 3) Postoperative Su-Ps skin tests showed a stronger response than preoperative tests regardless of the patients' stage, when patients received OK-432 treatment. The Su-Ps skin test reaction seemed to be well-correlated with the patients' immune status as above, so that this test can be chosen for evaluation of immunotherapy.