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Factor V deficiency and antenatal intraventricular haemorrhage

Serial obstetric ultrasound showed the development of asymmetrical ventricular dilatation between 28 and 32 weeks' gestation. After delivery at 38 weeks, progressive ventricular dilatation required a ventriculo-atrial shunt. Investigation of postoperative bleeding into the cerebral ventricles consistently showed factor V values of only two per cent.

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