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[A new structural analog of human insulin-- [glutamine-B30] insulin]

Iu P Shvachkin, S P Krasnoshchekova, A M Nikitina

Bioorganicheskaia Khimiia

|May 1, 1984

Abstract:

A new structural analogue of human insulin, [glutamine-B30]insulin, has been prepared by enzymatic-chemical means. This analogue differs from natural hormone by substitution of the ThrB30 residue. Biological activity of the [glutamine-B30]insulin is 100% in the mouse convulsion assay.

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