Proteolytic activity and calcium concentration in muscle wasting conditions

The Authors studied the role of proteolytic activity in specimens from denerved and dystrophic human muscles. The Calcium ions concentration was determined in the same samples, for evaluating the possibility of a correlation between these parameters. A significative increase in proteolytic activity was demonstrated for denerved and dystrophic muscles. Calcium ion's concentration was decreased in atrophic muscles compared to controls. No correlation was possible between the two parameters.