Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cancer chemotherapy. Progress and expectations, 1984.

B A Chabner, R L Fine, C J Allegra

    Cancer
    |December 1, 1984
    PubMed
    Summary

    Discovering new anticancer drugs and optimizing existing treatments are revolutionizing cancer care. Research focuses on novel screening, drug analogs, and pharmacokinetic strategies to improve patient outcomes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Phase I/II multicenter study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD4877 in patients with refractory acute myeloid leukemia.

    Investigational new drugs·2011
    Same author

    Cytidine and deoxycytidylate deaminase inhibition by uridine analogs.

    Biochemical pharmacology·2010
    Same author

    N-(phosphonacetyl)-L-aspartate and calcium leucovorin modulation of fluorouracil administered by constant rate and circadian pattern of infusion over 72 hours in metastatic gastrointestinal adenocarcinoma.

    Annals of oncology : official journal of the European Society for Medical Oncology·2002
    Same author

    Terrorism and cancer.

    The oncologist·2001
    Same author

    Complementary, alternative, integrative, or unconventional medicine?

    The oncologist·2001
    Same author

    Bleeding diathesis in multiple myeloma.

    Journal of hematotherapy & stem cell research·2001

    Area of Science:

    • Oncology
    • Pharmacology
    • Drug Discovery

    Background:

    • Cancer drug treatments have significantly advanced patient care.
    • New therapies offer hope for previously untreatable tumors.
    • Chemotherapy enhances the efficacy of surgery and radiotherapy.

    Purpose of the Study:

    • To explore novel anticancer drug discovery avenues.
    • To enhance the effectiveness of established chemotherapy agents.
    • To assess the impact of biochemical pharmacology on clinical protocols.

    Main Methods:

    • Utilizing new screening systems with human tumor material.
    • Developing improved analogs of anthracycline and platinum-based drugs.
    • Applying pharmacokinetic principles for targeted drug delivery.

    Main Results:

    • Promising results with new drugs in difficult-to-treat cancers.
    • Enhanced effectiveness of existing treatments through advanced delivery.
    • Improved understanding of drug action, resistance, and interactions.

    Conclusions:

    • Novel drug discovery and development are crucial for advancing cancer treatment.
    • Optimizing drug delivery and understanding resistance mechanisms improve clinical outcomes.
    • Biochemical pharmacology significantly impacts the design of effective cancer treatment protocols.

    Related Experiment Videos