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[Risks in pregnancy after kidney transplantation].
Deutsche Medizinische Wochenschrift (1946)
|November 9, 1984
Summary
Pregnancies after renal transplantation can lead to fetal growth retardation, possibly due to corticosteroids and toxaemia. Close monitoring is crucial to minimize risks for mother and child.
Area of Science:
- Nephrology
- Obstetrics
- Genetics
Context:
- Pregnancy following renal transplantation presents unique challenges for both mother and fetus.
- Supervised pregnancies in women with kidney transplants require careful management.
Purpose:
- To investigate the outcomes of pregnancies in women who have undergone renal transplantation.
- To identify potential risks and contributing factors to fetal growth retardation in this population.
Summary:
- Two women experienced four pregnancies post-renal transplant, with all resulting in fetal growth retardation and premature delivery.
- Corticosteroid therapy and increased toxaemia incidence are likely causes of growth retardation.
- While immunosuppressants showed no significant teratogenic risk, a potential mutagenicity risk is noted, evidenced by a Turner's syndrome case.
Impact:
- Highlights the need for interdisciplinary monitoring to manage risks associated with pregnancy after kidney transplantation.
- Informs clinical practice regarding the careful management of pregnant transplant recipients.