[Adaptive T-lymphocyte differentiation in an allogeneic environment]

Some patterns of adaptive changes of the hemopoietic stem cells in allogenic environment and the functional activity and specificity of cytotoxic T-lymphocytes developing from them and responsible for the inactivation of allogenic hemopoietic stem cells were studied on the radiation chimaeras. The allogenic environment did not prevent the functional maturation of these T-lymphocytes. The phenotype of T-lymphocytes matured under the conditions of allogenic recipient is similar but not identical with that of lymphocytes of the recipient mouse strain.