Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antibiotic prophylaxis in surgery.

R Platt

    Reviews of Infectious Diseases
    |November 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Perioperative antibiotic prophylaxis is common in hospitals, with proven benefits in some surgeries. Further research is needed to confirm its effectiveness, optimal use, and impact on patient outcomes and costs, especially for cardiovascular procedures.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Probabilistic Multiple-Bias Modeling Applied to the Canadian Data From the Interphone Study of Mobile Phone Use and Risk of Glioma, Meningioma, Acoustic Neuroma, and Parotid Gland Tumors.

    American journal of epidemiology·2017
    Same author

    Real World Data in Adaptive Biomedical Innovation: A Framework for Generating Evidence Fit for Decision-Making.

    Clinical pharmacology and therapeutics·2016
    Same author

    Impact of oral meloxicam and long-distance transport on cell-mediated and humoral immune responses in feedlot steers receiving modified live BVDV booster vaccination on arrival.

    Veterinary immunology and immunopathology·2016
    Same author

    Regulation of sodium excretion in normal, and salt-depleted subjects.

    Clinical science·2014
    Same author

    Heredity.

    The Medico-legal journal·2014
    Same author

    Sodium and potassium excretion in chronic renal failure.

    Clinical science·2014
    Same journal

    Fatal necrotizing otitis externa in a patient with AIDS.

    Reviews of infectious diseases·1991
    Same journal

    Use of the polymerase chain reaction for the specific and direct detection of Clostridium difficile in human feces.

    Reviews of infectious diseases·1991
    Same journal

    A new case of meningitis due to Pasteurella multocida.

    Reviews of infectious diseases·1991
    Same journal

    Disseminated pelvic actinomycosis presenting as metastatic carcinoma: association with the progestasert intrauterine device.

    Reviews of infectious diseases·1991
    Same journal

    Genetically engineered attenuated herpes simplex viruses.

    Reviews of infectious diseases·1991
    Same journal

    Role of altered drug metabolism in virus-drug interactions.

    Reviews of infectious diseases·1991
    See all related articles

    Area of Science:

    • Infectious Disease
    • Hospital Antibiotic Stewardship
    • Surgical Prophylaxis

    Background:

    • Perioperative prophylaxis represents a significant portion of hospital antibiotic usage.
    • Clinical evidence supports its efficacy in procedures like hysterectomy, cesarean delivery, colorectal, and orthopedic surgeries.
    • The efficacy of prophylaxis in cardiovascular surgery requires more rigorous evaluation despite its widespread use due to severe infection risks.

    Purpose of the Study:

    • To review the current evidence on perioperative antibiotic prophylaxis.
    • To identify gaps in knowledge regarding its impact on postoperative mortality, hospitalization duration, and medical costs.
    • To highlight areas for future research, including efficacy in various surgical settings and optimal antibiotic selection.

    Main Methods:

    Related Experiment Videos

    • Review of existing clinical studies and available data on perioperative antibiotic prophylaxis.
    • Analysis of the impact of prophylaxis on patient outcomes and healthcare costs.
    • Theoretical consideration of antibiotic properties, such as long half-lives, for prophylactic use.

    Main Results:

    • Prophylaxis is effective in specific surgical contexts but requires further rigorous evaluation for cardiovascular surgery.
    • Available data suggest potential reductions in mortality and overall costs under certain conditions.
    • Limited information exists on the impact of prophylaxis on postoperative morbidity and hospitalization duration.

    Conclusions:

    • Perioperative antibiotic prophylaxis is a critical area in hospital antibiotic use with established benefits in some procedures.
    • Further research is essential to determine optimal agents, regimens, and efficacy across diverse surgical settings, particularly cardiovascular surgery.
    • Understanding the full impact on morbidity, mortality, and costs is crucial for refining antibiotic stewardship protocols.