A new topical antifungal drug: tioconazole

Following 4 weeks of treatment, 32 of 35 tioconazole treated patients (91.4%) and 29 of 34 miconazole treated patients (85.3%) achieved clinical and mycologic cures. At follow-up four weeks after completion of treatment, 29 of 31 tioconazole treated patients (93.5%) and 25 of 28 miconazole treated patients (89.3%) remained cured. There was no significant difference between clinical, mycologic or clinical plus mycologic response to the two medications. The 96.2% positive culture correlation in this study is attributed to the selection of multiple culture sites.