[Basic and clinical studies on serum CEA levels using a new CEA-EIA (double monoclonal) kit]

Serum CEA levels were measured in normal subjects and in patients with benign and malignant diseases using a new Abbott CEA-EIA (double monoclonal) kit. The results of basic and clinical studies indicated that the correlation coefficient between serum CEA levels measured by a polyclonal CEA kit and serum CEA levels by the new kit was r = 0.976, and the reproducibility, stability and simplicity of this new kit were superior. The CEA levels were 1.68 + 0.11 ng/ml in normal subjects, and significant differences were shown between the two sexes, 1.81 + 1.67 ng/ml in the patients with benign diseases and a true positive rate of more than 7.0 ng/ml CEA levels was seen in 24.1% of the patients with malignant diseases. High positive rates were observed in patients with neoplasms, of the biliary tract and pancreas, then the colon, esophagus and stomach.