Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pyogenic liver abscess--a neglected diagnosis.

N L Sandford, R A Bradbear, L W Powell

    Australian and New Zealand Journal of Medicine
    |October 1, 1984
    PubMed
    Summary

    Pyogenic liver abscess diagnosis is often delayed, especially in elderly patients, leading to high mortality. Early diagnosis significantly improves survival rates for this serious condition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Arthropathy in hereditary haemochromatosis segregates with elevated erythrocyte mean corpuscular volume.

    Scandinavian journal of rheumatology·2020
    Same author

    Boron based separations for in situ recovery of L-erythrulose from transketolase-catalyzed condensation.

    Biotechnology and bioengineering·2008
    Same author

    Patient-focused outcomes following detection in a hospital-based screening programme for C282Y haemochromatosis.

    Internal medicine journal·2008
    Same author

    Use of community genetic screening to prevent HFE-associated hereditary haemochromatosis.

    Lancet (London, England)·2005
    Same author

    HFE gene and hemochromatosis.

    Journal of gastroenterology and hepatology·2004
    Same author

    A novel mutation in ferroportin1 is associated with haemochromatosis in a Solomon Islands patient.

    Gut·2003

    Area of Science:

    • Medicine
    • Hepatology
    • Infectious Diseases

    Background:

    • Pyogenic liver abscess (PLA) is a serious intra-abdominal infection with significant morbidity and mortality.
    • Historical data suggests challenges in PLA diagnosis and management, particularly in specific patient demographics.

    Purpose of the Study:

    • To review the clinical features, management, and outcomes of patients with pyogenic liver abscess.
    • To identify factors contributing to mortality and to emphasize the importance of timely diagnosis.

    Main Methods:

    • Retrospective review of 25 patients with pyogenic liver abscess admitted to a single tertiary hospital.
    • Analysis of patient demographics, clinical presentation, diagnostic methods, treatment, and outcomes.

    Main Results:

    • The overall mortality rate was 32%.
    • All patients diagnosed prior to death survived, highlighting the critical role of early diagnosis.
    • Patients with a history of biliary obstruction or surgery had a higher mortality rate (6/7 deaths).
    • Older patients who died were significantly older than survivors, possibly due to misdiagnosis as malignancy.

    Conclusions:

    • High mortality from pyogenic liver abscess is primarily attributed to diagnostic delays and lack of clinical awareness, not inadequate treatment.
    • Clinicians should maintain a high index of suspicion for liver abscess, even when initial investigations are inconclusive.
    • Prompt diagnosis and intervention are crucial for improving patient survival rates in pyogenic liver abscess cases.

    Related Experiment Videos