The use of subcutaneously implanted araldite disks for microstructural studies of inflammatory macrophages

Subcutaneously implanted epoxy resin disks can be used instead of glass coverslips in mice to recruit inflammatory macrophages. Implanted araldite disks exhibited large numbers of macrophages on both surfaces which could be observed conveniently by light and phase contrast microscopy. Most importantly, the disks can be embedded directly in an araldite mixture for the preparation of thin sections for electron microscope examination.