99Tcm-TDG renography with deconvolution analysis: a comparative study with 99Tcm-DTPA and 123I-hippuran

TDG has been compared with hippuran and DTPA in normal subjects and the derived gamma camera renograms of both the whole kidney and parenchymal regions subjected to deconvolution analysis using the matrix algorithm. The transit time of TDG was found to be longer than both hippuran and DTPA. The parenchymal mean transit time of TDG was 3.0 +/- 0.6 min (mean +/- S.D.). That of hippuran was 2.2 +/- 0.7 min and DTPA, 2.6 +/- 0.5 min. It is thought that a small fraction of the TDG is bound to the renal parenchyma thus prolonging both the mean and maximum transit times.