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Effect of theophylline on myocardial adenylate cyclase activity
Experientia
|April 15, 1978
Abstract:
Theophylline (0.001-10.0 mM) did not increase but rather decrased adenylate cyclase activity (AC) of guinea-pig auricles. Isoprenaline (1-100 microgram) and sodium fluoride (0.3-10.0 mM) stimulated AC in a concentration-dependent manner.