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Automated Multiplex Immunofluorescence Panel for Immuno-oncology Studies on Formalin-fixed Carcinoma Tissue Specimens
Published on: January 21, 2019
Recent progress in the immunohistochemistry of solid tumors
1Division of Anatomic Pathology, City of Hope National Medical Center, Duarte, CA 91010.
Improved, more sensitive, immunohistochemical methods and the development of monoclonal antibodies are simplifying the task of solving problems in the diagnosis of tumors in surgical pathology. Presented in this paper is our experience with the antibodies most frequently used in our laboratory to solve common problems in the surgical pathology of solid neoplasms. These are antibodies to keratins, leukocyte common antigen, protein S100, milk fat globule-derived antigen, and antibodies to basal lamina antigens.
Improved, more sensitive, immunohistochemical methods and the development of monoclonal antibodies are simplifying the task of solving problems in the diagnosis of tumors in surgical pathology. Presented in this paper is our experience with the antibodies most frequently used in our laboratory to solve common problems in the surgical pathology of solid neoplasms. These are antibodies to keratins, leukocyte common antigen, protein S100, milk fat globule-derived antigen, and antibodies to basal lamina antigens.
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