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Role of cryptic genes in microbial evolution.

B G Hall1, S Yokoyama, D H Calhoun

  • 1Biological Sciences Group, University of Connecticut, Storrs 06268.

Molecular Biology and Evolution
|December 1, 1983
PubMed
Summary
This summary is machine-generated.

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Cryptic genes, phenotypically silent DNA, can be activated by genetic mechanisms, providing microbes with an adaptable genetic reservoir for future evolution. These genes are preserved to enhance species

Area of Science:

  • Microbial genetics
  • Evolutionary biology
  • Molecular biology

Background:

  • Cryptic genes are DNA sequences that are not typically expressed.
  • These genes can be activated by various genetic mechanisms like mutation or recombination.
  • Their role in microbial adaptation and evolution is under investigation.

Purpose of the Study:

  • To propose a hypothesis for microbial adaptation and evolution via the mutational activation of cryptic genes.
  • To explore the mechanisms that prevent the loss of cryptic genes.
  • To highlight the significance of cryptic genes as an endogenous genetic reservoir.

Main Methods:

  • Review of microbial literature on biochemical evolution, physiology, and taxonomy.
  • Development of a mathematical model to analyze gene preservation.

Related Experiment Videos

  • Presentation of evidence supporting the hypothesis.

    • Main Results:

    • Cryptic genes can be activated in a subset of a population through genetic events.
    • Mechanisms exist that effectively prevent the loss of cryptic genes.
    • A mathematical model supports the persistence of these genes.

    Conclusions:

    • Cryptic genes are a vital component of the genetic repertoire.
    • Their activation provides a mechanism for rapid adaptation independent of genetic exchange.
    • Cryptic genes enhance the adaptive potential and evolutionary capacity of microbial species.