Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multicystic ovaries in primary hypothyroidism.

A N Lindsay, M L Voorhess, M H MacGillivray

    Obstetrics and Gynecology
    |April 1, 1983
    PubMed
    Summary

    Severe primary hypothyroidism in girls is linked to multicystic ovaries. Thyroid replacement therapy rapidly resolved ovarian cysts and normalized luteinizing hormone levels, suggesting a strong connection between thyroid function and ovarian health.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Unrecognized persistence of beta-hydroxybutyrate in diabetic ketoacidosis.

    Endocrine research·2001
    Same author

    Growth hormone use in pediatric growth hormone deficiency and other pediatric growth disorders.

    The American journal of managed care·2001
    Same author

    Growth hormone use in transitioning patients--clinician and payer concerns.

    The American journal of managed care·2001
    Same author

    The basics for the diagnosis and management of short stature: a pediatric endocrinologist's approach.

    Pediatric annals·2000
    Same author

    Growth hormone therapy in childhood-onset growth hormone deficiency: adult anthropometric and psychological outcomes.

    Endocrine·2000
    Same author

    Current dosing of growth hormone in children with growth hormone deficiency: how physiologic?

    Pediatrics·1998

    Area of Science:

    • Pediatric Endocrinology
    • Reproductive Endocrinology
    • Medical Imaging

    Background:

    • Primary hypothyroidism is a condition affecting thyroid hormone production.
    • Multicystic ovaries are characterized by multiple small cysts within the ovaries.
    • Hormonal imbalances can impact ovarian morphology and function in young females.

    Purpose of the Study:

    • To investigate the prevalence of multicystic ovaries in girls with severe primary hypothyroidism.
    • To assess the effect of thyroid replacement therapy on ovarian cysts and hormonal levels.
    • To explore the relationship between hypothyroidism and ovarian abnormalities in pediatric patients.

    Main Methods:

    • Pelvic ultrasound examinations were performed on girls diagnosed with primary hypothyroidism.
    • Hormonal assays, including plasma luteinizing hormone (LH) levels, were conducted.
    • Luteinizing hormone-releasing hormone (LHRH) testing was performed in a subset of patients.

    Main Results:

    • Nine out of 12 girls (75%) with severe primary hypothyroidism presented with multicystic ovaries.
    • Thyroid replacement therapy led to rapid resolution of ovarian cysts.
    • Elevated or high-normal LH levels decreased significantly after thyroid hormone treatment.

    Conclusions:

    • Pelvic ultrasound reveals a high frequency of multicystic ovaries in girls with primary hypothyroidism.
    • Thyroid replacement therapy is effective in resolving these ovarian cysts and normalizing hormonal profiles.
    • The findings highlight a significant link between thyroid dysfunction and ovarian development in pediatric patients, though the exact pathogenesis requires further investigation.

    Related Experiment Videos