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Updated: Aug 8, 2026

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 11, 2013
[Changes in cell mitosis under the influence of antigenically different strains of respiratory syncytial virus]
Abstract:
A peculiar effect on mitosis of RH cells of the reference Long strain and strain No. 14 of respiratory syncytial virus isolated during a rise of the incidence of acute respiratory diseases in Kharkov was observed. The Long strain affected mostly the qualitative and strain No. 14 the quantitative aspects of cell mitosis. The character of pathological mitoses under the influence of the Long strain indicated more considerable impairment of the mitotic apparatus of the cells than that caused by the strains No. 14. It is suggested that the peculiarities of the effect of the two respiratory syncytial virus strains on cell mitosis are associated with the structural and antigenic differences in the strains circulating in various geographic zones.
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