Three cases of choriocarcinoma (author's transl)

Report on three cases of choriocarcinoma which showed interesting features. In the first case a living male infant was delivered two years following chemotherapy for choriocarcinoma and the infant showed no chromosomal abnormalities. In the second case a choriocarcinoma developed three years following a post-partum tubal ligation and the localized tumor was successfully treated by hysterectomy without chemotherapy. In the third case the uterine tumour was refractory to chemotherapy with Actinomycin D and methotrexate and required a hysterectomy. The value of HCG and HPL titres in the differential diagnosis and the value of the microscopic results of the currettings are discussed. The possibility of chromosomal damage to infants born following chemotherapy of the mother is mentioned.