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Pharmaceutical considerations of nitroglycerin.

A Yacobi, A H Amann, D M Baaske

    Drug Intelligence & Clinical Pharmacy
    |April 1, 1983
    PubMed
    Summary

    This review consolidates information on new nitroglycerin (NTG) dosage forms and delivery systems to prevent confusion. It covers analytical techniques, drug interactions, and clinical pharmacokinetics, highlighting research gaps.

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    Area of Science:

    • Pharmaceutical Sciences
    • Pharmacology
    • Drug Delivery Systems

    Background:

    • Recent advancements have introduced novel pharmaceutical uses and delivery systems for nitroglycerin.
    • These innovations have led to potential confusion regarding the appropriate application of nitroglycerin products.

    Purpose of the Study:

    • To consolidate and clarify information on nitroglycerin's pharmaceutical applications, delivery systems, and clinical use.
    • To serve as a comprehensive resource for healthcare professionals and researchers.

    Main Methods:

    • Review of analytical techniques for quality control and pharmacokinetic studies of nitroglycerin.
    • Examination of nitroglycerin interactions with packaging and plastic delivery devices.
    • Synthesis of current knowledge on clinical pharmacy and pharmacokinetics of nitroglycerin.

    Main Results:

    • Identified various analytical methods for nitroglycerin quality control and pharmacokinetic assessment.
    • Detailed interactions between nitroglycerin and common packaging/delivery materials.
    • Provided an updated overview of clinical pharmacy and pharmacokinetic data for nitroglycerin.

    Conclusions:

    • The review aims to reduce confusion surrounding new nitroglycerin formulations and delivery systems.
    • It provides a foundation for informed choices regarding nitroglycerin use and identifies areas for future research.

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