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Updated: Aug 12, 2026

In Vitro Culture of Epithelial Cells from Different Anatomical Regions of the Human Amniotic Membrane
Published on: November 28, 2019
Tamm-Horsfall glycoprotein in human amniotic fluid
Abstract:
Radioimmunoassay of material cross-reacting with urinary Tamm-Horsfall glycoprotein in human amniotic fluid was carried out. The cross-reacting material was shown to be identical with urinary Tamm-Horsfall glycoprotein by double immunodiffusion and by crossed immunoelectrophoresis. The concentrations of the substance from 16-25 weeks pregnancy were found to increase from average levels of 0.9 mg . l(-1) to 4.9 mg . 1(-1) over this period. The concentrations were considerably higher (up to 33 mg . l(-1) close to term. Measurements of the glycoprotein in amniotic fluid may be a useful index for development of renal function in the foetus.
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