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Related Experiment Videos

Three-year experience with NORPLANT subdermal contraception.

I Sivin, F A Sanchez, S Diaz

    Fertility and Sterility
    |June 1, 1983
    PubMed
    Summary

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    NORPLANT subdermal implants containing levonorgestrel demonstrated a low cumulative pregnancy rate of 0.7 per 100 women over 3 years. Continuation rates were 44.6 per 100, with users experiencing irregular menstruation and moderate hemoglobin increases.

    Area of Science:

    • Reproductive Health
    • Contraception
    • Pharmacology

    Background:

    • Subdermal implants represent a significant advancement in long-acting reversible contraception.
    • Levonorgestrel implants offer a progestin-only method for family planning.
    • Understanding the efficacy and side effect profile of NORPLANT is crucial for clinical practice.

    Purpose of the Study:

    • To evaluate the efficacy and side effects of NORPLANT subdermal implants.
    • To assess user continuation rates for NORPLANT over a 3-year period.
    • To compare NORPLANT's safety profile with intrauterine devices.

    Main Methods:

    • A two-phase study involving 816 women using NORPLANT subdermal implants.
    • Data collection on pregnancies, continuation rates, menstrual patterns, hemoglobin levels, and blood pressure.
    Keywords:
    Acceptor CharacteristicsAcneAge FactorsBlood PressureBody WeightCentral Nervous System EffectsComparative StudiesContraceptionContraception ContinuationContraception TerminationContraceptive AgentsContraceptive Agents, FemaleContraceptive Agents, ProgestinContraceptive Agents--administraction and dosageContraceptive ImplantsContraceptive MethodsDepressionDizzinessEvaluationFamily PlanningFamily Size, IdealFatigueHeadacheHemoglobin LevelHepatic EffectsInfectionsIudIud, Copper ReleasingLevonorgestrel--administraction and dosageMenstruation DisordersMetrorrhagiaNauseaNervousnessParityPregnancy RateReproductive Control AgentsResearch MethodologySizeStudies

    Related Experiment Videos

  • Comparative analysis with TCu 200 intrauterine device users.

    • Main Results:

    • A cumulative net pregnancy rate of 0.7 per 100 women after 3 years.
    • First-segment continuation rate of 44.6 per 100 at 3 years.
    • Irregular menstruation was common, but average bleeding days and episodes remained normal. Hemoglobin levels increased moderately. Blood pressure profiles were similar to TCu 200 IUD users.

    Conclusions:

    • NORPLANT subdermal implants are highly effective in preventing pregnancy.
    • User continuation rates suggest a manageable side effect profile for many women.
    • NORPLANT presents a viable contraceptive option with a safety profile comparable to IUDs for certain parameters.