Amyloid deposition in immunoblastic lymphadenopathy

Two cases of immunoblastic lymphadenopathy are reported that in addition to having the usual histologic and electron microscopic appearance previously described exhibit perivascular and intersitial green polarization when stained with Congo red, indicating amyloid deposition. Electron microscopic examination confirmed the light microscopic findings. This finding may have significance in regard to etiology, progression, and treatment of this disease entity.