[Electron microscopic studies of Reinke oedema (author's transl)]

With the electron microscope, changes in the epithelium and subepithelial tissue in Reinke's oedema are more clear. An intense widening of the intercellular spaces is observed, with the presence of a strongly electron dense substance. In some cells, especially in the cells of the stratum spinosum and in the endothelial cells of the capillary vessels, intracytoplasmic cystic formations are observed, which in some cases are located in nuclear invaginations. However, these cystic formations can give a false impression that they are intranuclear if an incorrect tissue section is made.