Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Experience with home parenteral nutrition.

B M Wolfe, W H Beer, J T Hayashi

    American Journal of Surgery
    |July 1, 1983
    PubMed
    Summary

    Home parenteral nutrition (HPN) therapy is a vital treatment for severe gastrointestinal conditions, but it frequently leads to complications. Careful patient selection and monitoring are crucial for managing this complex therapy.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Association between Cognitive Function and Clustered Cardiovascular Risk of Metabolic Syndrome in Older Adults at Risk of Cognitive Decline.

    The journal of nutrition, health & aging·2020
    Same author

    Review article: the evidence that vancomycin is a therapeutic option for primary sclerosing cholangitis.

    Alimentary pharmacology & therapeutics·2018
    Same author

    PI3Kδ inhibition elicits anti-leukemic effects through Bim-dependent apoptosis.

    Leukemia·2016
    Same author

    Occupational differences in US Army suicide rates.

    Psychological medicine·2015
    Same author

    BCR-signaling-induced cell death demonstrates dependency on multiple BH3-only proteins in a murine model of B-cell lymphoma.

    Cell death and differentiation·2015
    Same author

    Understanding the elevated suicide risk of female soldiers during deployments.

    Psychological medicine·2014

    Area of Science:

    • Gastroenterology
    • Clinical Nutrition
    • Internal Medicine

    Background:

    • Home parenteral nutrition (HPN) is a critical intervention for patients with debilitating gastrointestinal disorders.
    • Indications for HPN include radiation enteritis, short bowel syndrome, Crohn's disease, and other malabsorption states.

    Purpose of the Study:

    • To evaluate the outcomes and complications associated with long-term home parenteral nutrition therapy.
    • To assess the efficacy and safety of HPN in managing catastrophic clinical situations.

    Main Methods:

    • A retrospective analysis of 29 patients receiving HPN for durations ranging from 1.5 to 52 months.
    • Data collected included primary diagnoses, complications, and patient outcomes (weaning, death, or ongoing therapy).

    Related Experiment Videos

    Main Results:

    • Seventeen patients (57%) experienced at least one complication, including intravenous catheter issues (9 patients) and metabolic disturbances (9 patients).
    • Nine patients died, 11 were successfully weaned off HPN, and 9 continue to receive HPN.
    • HPN proved useful in preparing patients for surgery, managing temporary malabsorption, and supporting permanent gastrointestinal failure.

    Conclusions:

    • Home parenteral nutrition is a valuable, albeit complex, therapeutic option for severe gastrointestinal failure.
    • Complications are common and can be life-threatening, necessitating vigilant management and patient selection.